18-25 Yaş Arası Bireylerden İzole Edilen Mayaların Biyofilm Oluşturma Kapasitesinin ve Antifungal Direncinin İn Vitro Olarak Değerlendirilmesi

Microbiota studies are an increasingly important issue today. In the literature, there limited on antifungal resistance and biofilm formation capacity of yeasts isolated from mouths young individuals. For this reason, our study was carried out with 133 yeast isolates 17 individuals between ages 18-25 in 2018-2020. When biofilm-forming capacities were examined, it determined that 99.25% producers by tissue culture plate method 66.92% tube method. One hundred thirty-three seven reference strains first evaluated against fluconazole agar disc diffusion The found to be susceptible fluconazole. According result, 20 strong selected isolates. Antifungal fluconazole, itraconazole, clotrimazole, amphotericin B nystatin gradient test strips. It resistant B, 18 antifungal. sensitivity itraconazole 14 clotrimazole 3 dose-dependent. As a azole group antifungals can used mainly treating oral infections.